Mounjaro: a new step in GLP-1 therapy

Starting a new weight loss medication is an exciting step. Especially when it involves something new, such as a GLP-1 medication. A better understanding of these medications—how they work and what results and side effects to expect—can provide peace of mind. In this blog, you can read more about Mounjaro, one of the GLP-1 medications prescribed to patients struggling with obesity.

What is Mounjaro?

Mounjaro, which contains the active ingredient tirzepatide, is an injectable medication. Mounjaro differs from other GLP-1 medications in that it acts on two receptors: GLP-1 and GIP. Both are hormones that influence appetite, blood sugar regulation, and fat burning. It is this dual action that ensures a more powerful and longer-lasting effect than traditional GLP-1 medications, such as semaglutide (known, for example, as Ozempicand Wegovy).

Why is Mounjaro more expensive than other GLP-1 medications?

The price of Mounjaro is higher than that of other GLP-1 medications, which naturally raises questions. There are three important reasons for this higher price:

1. An innovative mechanism of action that activates two receptors

Mounjaro acts on both the GLP-1 and GIP receptors. This combined approach is new. As a result, the medication not only suppresses appetite but also improves insulin sensitivity and promotes fat burning. This additional effect makes the development of the medication more complex. However, it is also more effective, which is reflected in the higher price.

2. Limited availability and high global demand

Because Mounjaro is still a relatively new medication, its production capacity is limited. At the same time, the global demand for effective weight loss medications has grown exponentially. This drives up the price. At Goodweigh, we work with a reliable Dutch pharmacy. This ensures you can be certain that you are receiving safe medication—not illegal or counterfeit products. Safety is always our top priority.

How does Mounjaro work?

Mounjaro helps your body reduce appetite in a natural way and process food more efficiently. It works in several different ways:

1. Slowing down gastric emptying

One of Mounjaro's key effects is slowing down the rate at which the stomach empties. Food stays in your stomach longer, which helps you feel full for an extended period. This helps you eat less without feeling constantly hungry.

2. Blood sugar regulation

Mounjaro stimulates insulin release when you eat, while simultaneously inhibiting the glucagon hormone, which normally raises your blood sugar. This keeps your blood sugar levels more stable and helps you avoid energy crashes.

3. Appetite suppression

By acting on the areas of the brain associated with hunger and satiety, Mounjaro reduces your appetite. Many people find that this decreases the urge to snack or overeat, even when triggered by emotional factors.

Treatment always begins with a low dose so your body can adjust to the medication gradually. The dose is then increased in stages based on your individual response. This titration schedule reduces the risk of side effects such as nausea, bloating, or fatigue. At Goodweigh, we guide this process step-by-step in collaboration with a Dutch physician.

Why a healthy diet remains important

It is important to understand that Mounjaro is not a miracle cure. It supports you, but it does not do the work alone. A healthy diet remains a crucial factor in achieving good long-term results.

1. A healthy diet reinforces Mounjaro's effect

By eating healthily, you work with your medication rather than against it. Fiber-rich foods, proteins, and healthy fats keep you full for longer. This helps reinforce Mounjaro's appetite-suppressing effect.

2. A healthy diet prevents deficiencies and symptoms

When you eat less, you automatically consume fewer nutrients. By consciously choosing vegetables, fruits, whole grains, and healthy fats, you ensure that your body still gets everything it needs—even while you are eating less.

3. You learn to adopt sustainable habits

Mounjaro helps you lose weight, but the ultimate goal is for you to be able to maintain your new lifestyle – even after you stop taking the medication. A healthy diet is key to this. It is not just a diet, but a lifestyle change that must be continued even after you stop using Mounjaro.